EndNote 21
EndNote 21 is a macOS reference management app for collecting research sources, organizing libraries, and creating citations and bibliographies.
What is EndNote 21?
EndNote 21 is a desktop reference manager for macOS that helps students, researchers, librarians, and academic writers collect, organize, search, and cite scholarly sources. It is used to build personal or shared reference libraries, attach and manage PDFs, annotate documents, and keep citation data organized across research projects. The app supports importing references from online databases and library catalogs, finding full text for available items, and formatting citations and bibliographies in many publication styles. EndNote 21 also integrates with writing workflows through Cite While You Write tools for Microsoft Word, with support for Word online and Google Docs features introduced in this version. Published by Clarivate, it is commonly used in universities, labs, and other research-heavy environments where accurate citation management is part of everyday work.
Key features
- Collect references from research databases and library catalogs
- Organize sources into searchable libraries, groups, and tags
- Attach, read, and annotate PDF articles alongside references
- Insert citations and build bibliographies in Microsoft Word
- Use citation tools with Word online and Google Docs workflows
- Find and format references using thousands of citation styles
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Inspect caches, support files, containers, and login items before cleaning.
Safety overview
Status: Safe
EndNote 21 is legitimate academic research software. It normally needs access to documents, PDFs, and Word files so you can manage references, attach articles, and insert citations while writing. If you sync libraries or use online features, some reference data and attachments may be stored with your account, so use your usual care with unpublished manuscripts or sensitive research files. Keep the app updated and remove local libraries only when you no longer need the citations, PDFs, and notes stored in them.
Recommendation: Keep EndNote 21 if you use it for academic writing, literature reviews, or bibliography management. Remove it only if you no longer need its reference libraries, Word citation tools, or attached PDFs, and export any libraries you want to keep first.
Common paths
/Applications/EndNote 21/EndNote 21.app
Support paths
~/Library/Application Support/EndNote
Preference paths
~/Library/Preferences/com.ThomsonResearchSoft.EndNote.plist~/Library/Preferences/com.IsiResearchSoft.EndNote.plist
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